Mystery ER is a medical reality program, created by Mike Mathis for the Discovery Health Channel. The show features reenactments of real-life medical mysteries, told through narration and interviews.
- Created by
- Jeffrey R. Daniels

Mystery ER is a medical reality program, created by Mike Mathis for the Discovery Health Channel. The show features reenactments of real-life medical mysteries, told through narration and interviews.
2 seasons · 14 episodes
Scared Stiff/Deadly Grind
Jul 14, 2008
SCARED STIFF When a single mother wakes up to find she can no longer walk, her doctors go looking for the elusive disease they suspect is afflicting her central nervous system. Despite aggressive treatment, the nightmare returns to take bac
Truth Be Told/Climbing for Life
Jul 21, 200860 min
"TRUTH BE TOLD" In 1978, during the height of the Cold War, a military wife suffers a sudden paralysis in her leg that defies explanation. As she slowly slips into a near-catatonic state, a team of military medical specialists investigates
Dead in Ten/Speed Bump
Jul 28, 2008
"DEAD IN TEN" When a young woman goes to the ER with severe abdominal pains, the doctors find a rare and virulent type of cancer that gives her ten years to live. There's something more to this mystery though and the woman must find what it
Desperate Measures/A Stinging Pain
Aug 4, 2008
"DESPERATE MEASURES" (a.k.a. "HOME INVASION") After starting a new life in a new apartment, the mother of a little girl notices her child is suffering from a burning rash. At first, doctors attribute it to the eczema she was born with, but
Eating Away/A Model's Malady
Aug 25, 2008
"EATING AWAY" An athletic swimmer gets attacks of near-paralytic exhaustion, after which his urine becomes strangely dark. Over the years his symptoms persist until the day he goes into the ER with symptoms of a cardiac arrest. One doctor f
Rash Decision/Inflamed
Sep 1, 2008
"RASH DECISION" A.K.A."IRRATIONAL SYNDROME" In 2006 an otherwise healthy college student comes down with a purple rash that literally spreads before his eyes. After a series of ER visits, the doctor narrows it down to one of eight possible